Naslov
Two Different Manifestations of Locked-In Syndrome

Autori
Golubović, Vesna ; Muhvić, Damir ; Golubović, Snježana ; Juretić, Mirna ; Sotošek, Vlatka

Izvornik
Collegium antropologicum (0350-6134) 37 (2013), 1; 313-316

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prethodno priopćenje, znanstveni

Ključne riječi
locked-in syndrome; posttraumatic locked-in syndrome; basilar thrombosis; anticoagulant therapy; antioedema therapy

Sažetak
Locked-in syndrome (LIS)is an entity that usually occur as consequence of the lesion of ventral part of pons. Etiology of locked-in syndrome can be vascular and nonvascular origin. Locked-in syndrome usally occurs as a consquence of thrombosis of intermedial segment of basilar artery that induces bilateral infarction of the ventrobasal part of the pons. Additionally, LIS can be caused by trauma which often leads to posttraumatic thrombosis of basilar artery. The incidence of locked-in syndrome is still unknown.The basic clinical features of locked-in syndrome are:qadriplegia (a consequence of disruption of corticospinal pathways located in ventral part of pons), different stages of paralysis of mimic musculature, paralysis of pharynx, tongue and palate with mutism and anarthria. The patient can not move, but is conscious and can communicate only by eye movements. Two patients with locked-in syndrome were present in this article. In the first case, the patient had classic locked-in syndrome that was first described by Plum and Posner.Other patient had incomplete form of locked-in syndrome which was first described by Bauer. In these two patients locked-in syndrome occured as a consequence of trauma. In the first patient locked-in syndrome was caused by direct contusion of ventral part of pons while in other patient locked-in syndrome was a consequence of posttraumatic thrombosis of vertebrobasilar artery. The introduction of anticoagulant therapy, besides the other measure of intensive therapy, has shown complete justification in the second patient. The gradual patial recovery of neurologic drficit has developed in the second patient without any additional complications.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA