Naslov
Epidemiology of malignant epidermal tumors and importance of national cancer registry

Autori
Strnad, Marija ;

Izvornik
Acta Dermatovenerologica Croatica (1330-027X) 7 (1999), 3;

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
epidemiology; epidermal tumors; cancer registry

Sažetak
Recent studies point to an increase in the prevalence of basal cell and squamous cell skin cancer in some country. Systematic data collection on these epidermal, mostly skin tumors is still lacking in most countries, probably due the fact that these are malignant tumors with most favorable prognosis, and beccause of high cost of cancer registry. Therefore, the prevalence of this type of cancer worldwide cannot be even approximately estimated. In addition, basal cell and squamous cell skin cancers are frequently recorded together in the registries of epidermal skin cancer, while some cases proceed unrecorded. In the USA alone, about one milion new cases and 1.900 deaths from basal cell or squamous cell skin cancer have been estimated to occur per year. Unfortunately, only data on deaths but not on new cases of this type cancer are available in Croatia. In 1990 and 1997, there wre 70 and 40 deths from nonmelanomatous malignant skin cancer, repectively, revealing a lower and decreasing skin cancer mortality. Basal cell carcinoma is the most common type of skin cancer in whites, its ratio to squamous cell cancer being 3:1. A majority of basal cell tumors develop on the sun exposed parts of the body, mostly in fairskinned (blue eyes and fair or red hair) individuals. Thus, the head, neck and face are most commonly involved. Basal cell cancer is rare in colored populations. Other risk factor include exposure to soon, tar, arsenic and ionizing radiation, positive family history, immunosuppressive conditions, chronic irradiation or inflammation, advanced age ( basal cell cancer and squamous cell cancer usually develop in idividuals older than 50 and 70, respectively,), existence of another primary malignoma, and viral carcinogens. Data on cancer incidence in the world, provided by the International Board for cancer research from Lyon, point to great differences among various geographics areas. The highest age-standardized rate has been recorded for Europeans in Harare, Zimbabwe (535.4/100 000 and 343.0/100 000 for men and women respectively), while it is much lower for Africans (only 4.0 and 4.3).

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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