Pregled bibliografske jedinice broj: 64032
The decrease of Na, K-ATPase activity in the renal cortex and medulla induced by enalapril
The decrease of Na, K-ATPase activity in the renal cortex and medulla induced by enalapril // Acta Pharmaceutica, 50 (2000), 1; 49-55 (međunarodna recenzija, članak, znanstveni)
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Naslov
The decrease of Na, K-ATPase activity in the renal cortex and medulla induced by enalapril
Autori
Matasić Rossini, Mirela ; Samaržija, Ita
Izvornik
Acta Pharmaceutica (1330-0075) 50
(2000), 1;
49-55
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Na+K+-ATPase; enalapril; kidney; cortex; medulla
Sažetak
In this study the influence of enalapril (1 mg kg-1 b. m.),
on the Na+K+-ATPase activity in samples of renal cortex
and medulla was investigated. The results showed that
after one-day treatment the Na;K-ATPase activity had
already decreased: in cortical samples the reduction was
16.4 ą 57% whereas in medullar ones it was 10.6 ą 4.9%
(n = 10) if compared to the controls. A seven-day treat-
ment with enalapril induced no additional effects in the
cortical samples, whereas the medullar decrement was
as high as 26.9% in comparison to the controls. A four-
teen-day treatment induced a decrease of Na+K+-ATPase
activity in the cortical and rnedullar samples of 48.6%
and 46.7%, respectively, in comparison to the control
group.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
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Časopis indeksira:
- Scopus
