Naslov
MICROBIAL ETHANOL PRODUCTION IN POST-MORTEM URINE SAMPLE

Autori
NESTIĆ, Marina ; KOVAČIĆ, Zdravko ; GUSIĆ, Stjepan ; MLINAREK, Tajana ; SARDELIĆ, Sanda ; SALAMUNIĆ, Ilza ; SUTLOVIĆ, Davorka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Abstracts of the 4th Croatian Congress of Toxicology (CROTOX 2012) / Želježić, Davor - , 2012, 48-48

Skup
Croatian Congress of Toxicology (CROTOX 2012)

Mjesto i datum
Primošten, Hrvatska, 02.10.2012. - 05.10.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
ethanol and acetone concentrations in blood and urine; ketoacidosis; prevention of post-mortem ethanol production; sodium fl uoride

Sažetak
We present a case in which post-mortem blood ethanol concentration was 0.02 g kg-1 and acetone concentration was 0.51 g kg-1 while urine ethanol concentration was 6.0 g kg-1 and acetone concentration was 0.63 g kg-1. The presence of acetone in blood and urine indicated the presence of ketoacidosis, which can lead to ketotic diabetic coma. The concentrations acetone may reach in diabetics are almost independent from the post-mortem interval. Sodium fl uoride was not added to the urine sample in which we continued to observe a remarkable increase in isopropyl alcohol concentration. The result was not logical and suggested that the alcohol concentration in urine was not due to consumption of alcoholic beverages. External contamination was excluded. Glucose levels were determined a few days after blood and urine samples were collected. Species of bacteria and yeasts, including Candida albicans, were isolated from both samples. A few days after the autopsy, we received the information that the patient suffered from Diabetes Mellitus and did not receive insulin therapy regularly. To prevent post-mortem ethanol production and thus making wrong assumptions of the cause of death, it is necessary to add sodium fl uoride in blood and urine samples from patients with diabetes.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija

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