Naslov
Non-paternity and genetic inconsistencies in cases of disputed fatherhood in DNA laboratory in Osijek, Croatia

Autori
Ćurić, Goran ; Mužar, Silvija ; Vrselja, Zvonimir ; Glavaš Obrovac, Ljubica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
The 8th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine: The book of abstracts / Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses - Zagreb : International Society for Applied Biological Sciences (ISABS), 2013, 177-177

ISBN
978-953-57695-0-7

Skup
The 8th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine

Mjesto i datum
Split, Hrvatska, 24.06.2013. - 28.06.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Non-paternity; fatherhood; paternity testing; forensics; STR loci

Sažetak
Uncertainty of paternity nowadays can be easily resolved with DNA testing. The method of DNA profiling used for determining whether two individuals have a biological parent–child relationship in Forensic DNA laboratories is based on PCR and the use of highly polymorphic short tandem repeats (STRs). The aim of this study is to establish (1) the rate of non-paternity in a sample from paternity testing laboratory, (2) association of non-paternity event with other available data and (3) type of inconsistencies between the obtained genotypes. The study is based on review of archive material from 248 cases of paternity testing during the 13 years (2001-2013) in Laboratory for DNA analysis in Medical school in Osijek, Croatia. Paternity testing was in 64.1% of cases ordered by the court (child as a plaintiff) and in 14.5% of cases requested privately by the father. Mothers` maiden name was found in 67.7% children, and in 12.5% of children had fathers` last name. Paternity testing was false in 13.3% of cases. Children with false paternity test were younger than children with positive paternity test (Me 0.41 years vs. Me 1.00 years ; p=0.049). Six mutations were observed within 3 480 allelic transfers at 15 STR-loci. Our non-paternity rate of 13.3% in population sample was among the lowest of published data from other paternity testing laboratories.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti

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