Naslov
Lupus profundus or lupus erythematosus panniculitis. A case report and review of literature.

Autori
Jajić, Ivo ; Jajić, Zrinka ; Grazio, Simeon ; Nemčić, Tomislav ; Belicza, Mladen

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 8 (2000), 4; 227-230

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, znanstveni

Ključne riječi
lupus profundus ; lupus erythematosus ; panniculitis ; skin diseases

Sažetak
Lupus profundus is a rare disease. It occurs independently as a separate entity or rarely along with discoid or systemic lupus erythematosus. In most cases, it is a disease of women between there thirties and sixties. Painful and bluish nodules develop in subcutaneous fat tissue ranging in diameter 1-2 cm. After one-month atrophy of skin and subcutaneous fat tissue occur with adherence of the skin to muscles and bones. In typical cases pathohistological finding is abundant of lymphocytes and histiocytes. Therapy consists of anti-malarial drugs alone or in combination with corticosteroids and occasionally cytotoxic drugs. We present female patient with 20-year duration of the disease manifesting continual progression with irreversible changes as well as resistance on therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA