Naslov
Investigation of Chemical Compounds, Antioxidant and Antimicrobial Properties of Teucrium arduini L. (Lamiaceae)

Autori
Kremer, Dario ; Košir, Iztok Jože ; Kosalec, Ivan ; Zovko Končić, Marijana ; Potočnik, Tanja ; Čerenak, Andreja ; Bezić, Nada ; Srečec, Siniša ; Dunkić, Valerija

Izvornik
Current Drug Targets (1389-4501) 14 (2013), 14; 1006-1014

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Antimicrobial activity ; antioxidant capacity ; essential oils ; phenolic compounds ; Teucrium arduni

Sažetak
In this paper chemical composition of the essential oil (analysed by GC and GC-MS), the content of phenolic compounds (analysed by HPLC), quantity of total phenols and total flavonoids (analysed by UV/Vis spectrophotometer), antioxidant and antimicrobial activities of ethanolic extracts were investigated in endemic Teucrium arduini L. in population of Mt Biokovo (Croatia). The oil was characterized by a high concentration of sesquiterpene hydrocarbons (70.4%) of which β-caryophyllene (35.2%) and germacrene D (18.7%) being the major compounds. Three phenolic compounds (quercetin, ferulic acid and rosmarinic acid) were identified and quantified in ethanolic extract of T. arduini using HPLC. The results also showed that T. arduini is a source of polyphenolic and other antioxidants with radical-scavenging and chelating properties. The ethanol extracts prepared from the leaf of T. arduini showed broad spectrum of antimicrobial activity on Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and Aspergillus brasiliensis, which are susceptible on concentration below or equal to 4.00 mg/mL, whilst Microsporum gypseum was resistant at investigated concentrations.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Farmacija, Biotehnologija

POVEZANOST RADA