Naslov
An Asian Trace in the Genetic Heritage of the Eastern Adriatic Island of Hvar

Autori
Šarić, Tena ; Šarac, Jelena ; Havaš Auguštin, Dubravka ; Novokmet, Natalija ; Rootsi, Siiri ; Deka, Ranjan ; Missoni, Saša ; Villems, Richard ; Rudan, Pavao

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
PROGRAM AND ABSTRACTS The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine / Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses - Zagreb : International Society for Applied Biological Sciences (ISABS), 2013, 223-223

ISBN
978-953-57695-0-7

Skup
The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine

Mjesto i datum
Split, Hrvatska, 24.06.2013. - 28.06.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Island of Hvar; Y chromosome; mtDNA; Q*-M424; founder effect; genetic drift

Sažetak
The Island of Hvar is situated in the central eastern Adriatic, and its relatively small rural population has been reproductively isolated thought history. Therefore, founder effects, genetic drift and inbreeding have had significant role in the shaping of current genetic diversity of Hvar Islanders. We analyzed Y-chromosome SNP markers of 412 Hvar islanders in high resolution, with the aim to investigate the current paternal genetic diversity. We found a relatively high frequency (6.1%) of unrelated male samples belonging to the Q*-M424 haplogroup, which is unusual for European populations. Interestingly, a previous study showed 9 individuals from Hvar with mitochondrial haplogroup F, which is almost absent in Europe. Both findings could indicate a certain connection with Asian populations, where these haplogroups are most common. This might be a result of several migratory events in the history, one of which could be linked to the ancient Silk Road, the other a consequence of the arrival of the Slavs, following the Avars, to the eastern Adriatic in the 6th century or due to the expansion of the Ottoman Empire in 16th to 18th century. The presence of these rare mitochondrial and Y-chromosome lineages are an example of founder effect and random genetic drift which, in this small island with a high degree of isolation and endogamy, had a strong impact on shaping the genetic diversity of the population.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Etnologija i antropologija

POVEZANOST RADA