Naslov
Bowl vs. Funnel supramolecular concept for Cu(I) Complexes within the Biomimetic Tris-imidazole Core

Autori
Gout, Jerome ; Višnjevac, Aleksandar ; Rat, Stéphanie ; Bistri, Olivia ; Le Poul, Nicolas ; Le Mest, Yves ; Reinaud, Olivia

Izvornik
European journal of inorganic chemistry (1434-1948) 16 (2013), 29; 5171-5180

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
copper coordination; resorcinarenes; biomimetic model

Sažetak
CuI coordination to a poly-imidazole core is of the most importance in biology since it is present in most enzymes as well as in peptides involved in pathological processes. Here, we report a detailed study relative to CuI binding to a tris-imidazole core constructed on a resorcinarene scaffold. NMR and IR spectrocopies as well as cyclic voltammetry have been used for characterizing the different species obtained in solution as a function of the presence/absence of exogenous ligands, mainly CO and MeCN, but also ClIt is shown that within the resorcinarene scaffold, the metal ion can switch from a dynamic 2-coordinate to a 4- coordinate environment upon binding to a - acceptor. Comparison to the previously reported calix[6]arene-based tris-imidazole Cu complexes highlights several key points: importance of the shape and size of the macrocycle forming a pocket in which the metal center is partly embedded, importance of the flexibility of the system undergoing induced-fit processes (calixarene) or not (resorcinarene), consequences on the affinity of the metal center for CO and MeCN in relation to its -back bonding capabilities, and finally, redox behavior.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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