Naslov
Lipoperoxidative events influence ochratoxin A biosynthesis in Aspergillus ochraceus during the interaction with Triticum durum seeds

Autori
Reverberi, Massimo ; Scarpari, Marzia ; Punelli, Federico ; Zjalic, Slaven ; Ricelli, Alessandra ; Fabbri, Anna A. ; Fanelli, Corrado

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
1st SIBV Annual Congress / - , 2009

Skup
1st SIBV Annual Congress

Mjesto i datum
Verona, Italija, 30.06.2009. - 02.07.2009

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
ochratoxin A; lipoperoxidase; wheat seeds

Sažetak
In different Aspergilli, lipoperoxidative events stimulate mycotoxin biosynthesis, conidiogenesis and sclerotia formation. A lox-like gene sequence (AoloxA ; DQ087531) has been found in Aspergillus ochraceus which presents an high homology (>95%) with a 15-arachidonate lox gene of A. fumigatus (XP_746844). To study the effect of oxylipins on morphogenesis and OTA biosynthesis and to investigate the interaction between wheat seeds and A. ochraceus during fungal colonization, an AoloxA null mutant, DAoloxA, has been generated. The results obtained show that lipoperoxidation in A. ochraceus, mainly driven by AoloxA, modulates morphogenesis, OTA biosynthesis and the interaction with the wheat seeds. Taken together these data suggest that a communication via oxylipins can be established between A. ochraceus and the wheat seeds as well as in A. nidulans/maize interaction. In conclusion, we postulate that some of the mechanisms that drive toxin biosynthesis and morphogenesis, mediated by fatty acids by-products, in A. nidulans, A. flavus and A. parasiticus are active also in A. ochraceus.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Biotehnologija

POVEZANOST RADA