Naslov
Evaluation of reliability of the three-part differential blood count obtained by the hematology analyzer

Autori
Petani, Sandra ; Topić, Elizabeta ; Turčić, Graciela

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Advances in Clinical Pathology 1 (1997), 2, suppl. 1 1 / Gonano, F. ; Lukač-Bajalo, J. ; Brguljan-Meško, P. ; Marc, J. - Udine : Eurostampa, 1997, 40-41

Skup
4th International Congress of Clinical Chemistry and Laboratory Medicine

Mjesto i datum
Bled, Slovenija, 22.05.1997. - 24.05.1997

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
MEK-8118K; Nihon Kohden; CD 1700CS; Abbott; hematology analyzers; comparability studies

Sažetak
The three-part differential blood count produced by the MEK-8118K (Nihon Kohden) and CD 1700CS (Abbott) hematology analyzers was compared to the reference manual method of microscopic leukocyte differentiation by the analysis of 398 normal and pathologic patient samples, whereby 129 samples were used for comparability studies on the MEK-8118K and 269 samples were used for comparability studies on the CD 1700CS analyzer. The study of the diagnostic performance of the differential blood count showed a good global sensitivity (91.1% for MEK-8118K and 92.1% for CD 1700CS) and specificity (92.0% for MEK-8118K and 88.6% for CD 1700CS), with a percentages of agreement of 92.3% for MEK-8118K and 91.1% for CD 1700CS, and with a low number of false negative results (3.1% for MEK-8118K and 5.6% for CD 1700CS). Evaluation of the suspect population flags for three-part differential blood count showed these flags to be a useful indication of pathologic changes in differential blood count and of the need of microscopic differentiation. Testing of sample stability showed that patient samples for three-part differential blood count analysis could be stored for up to 8 hours. After 8 hour sample storage, changes in all of the three leukocyte subpopulations were observed ; a pronounced decrease of neutrophil and an increase in lymphocyte and mid-size cell percentages.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA