Naslov
Thyroglobulin determination, neck ultrasonography and iodine-131 whole-body scintigraphy in differentiated thyroid carcinoma

Autori
Franceschi, Maja ; Kusić, Zvonko ; Franceschi, Dinko ; Lukinac, Ljerka ; Rončević, Sanja

Izvornik
The Journal of nuclear medicine (0161-5505) 37 (1996), 3; 446-451

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
thyroid carcinoma ; thyroglobulin ; neck ulstrasonography ; iodine-131 ; whole-body scintigraphy

Sažetak
Increased levels of thyroglobulin (ranging from 12 to >600 ng/ml) were measured in 40 of 55 (73%) patients with metastases or local recurrences. Ultrasonography revealed occult neck masses that were not detected by other methods. Neck ultrasonography and ultrasound- guided biopsy were positive for malignancy in 23 patients. Thyroglobulin levels were undetectable in 12 (52%) of these patients and 131-J whole-body scintigraphy was negative in 19 (83%) of them. The combined use of three diagnostic modalities (measurement of serum thyroglobulin, neck ultrasonography with ultrasound-guided biopsy for detecting recurrences of carcinoma in the neck region and 131-J whole-body scintigraphy) appears to give the best results in the follows-up patients with differentiated thyroid carcinoma.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA