Naslov
Mould growth and aflatoxin accumulation in the presence of newly synthesized analogues of dehydroacetic acid

Autori
Tkalčević, Ksenija ; Duraković, Senadin ; Sušnik-Rybarski, Ivana ; Duraković, Zijad ; Pospišil, Olga ; Radić, B. ; Brečević, Ljerka

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
DHA; BrDHT; antifungal; and antiaflatoxigenic activity; Aspergillus parasiticus; aflatoxin B1 and G1

Sažetak
Dehydroacetic acid (DHA) and its newly synthesized analogues, 4-hydroxy-3(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (DHT) and 5-bromo-4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (BrDHT), were tested for antifungal and antiaflatoxigenic activity against Aspergillus parasiticus NRRL 2999. DHT and DHA concn of 3, 0 µM and 6, 0 µM, respectively, stimulated mould growth and aflatoxin B1 and G1 synthesis, but concn >30, 0µM produced an inhibitory effect. In the presence of low BrDHT concn mould growth decreased by 70% and toxin concn by 85 and 90%, respectively.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA