Naslov
Paget's disease as a cause of severe paraplegia, with complete recovering after alendronate therapy: case report.

Autori
Krpan, Dalibor ; Buljan Culej, Jasminka ; Dogan Darko ; Oršolić Krešo ; Lajtman, Zoran.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Calcified Tissue International / Civitelli, Roberto ; Hruska, Keith ; Ralston, Stuart H. - New York (NY) : Springer, 2002, 285-285

Skup
29th European Symposium on Calcified Tissues

Mjesto i datum
Zagreb, Hrvatska, 25.05.2002. - 29.05.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Paget's disease; severe paraplegia; alendronate therapy

Sažetak
We report a clinical case of unusual clinical and radiological features of Paget's disease in a 42-year old, previously healthy Caucasian woman who suffered of severe paraplegia. The patient was treated daily with 10 mg alendronate and 0.25 mcg calcitriol. Six months later the patient was able to stand up and after eight months complete recovery has been achieved. Subsequent analyses indicated: normalization of bone turnover, less osteoplastic foci on x-ray images of vertebrae and pelvis, regression of hyperosification in areas of vertebrae Th XI and Th XII on NMR images and improved mobility of the patient.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA