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Pregled bibliografske jedinice broj: 612968

An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid

Petrović Peroković, Vesna; Ribić, Rosana; Prugovečki, Biserka; Matković-Čalogović, Dubravka; Tomić, Srđanka
An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid // Croatica chemica acta, 85 (2012), 4; 419-423 doi:10.5562/cca2122 (međunarodna recenzija, članak, znanstveni)

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Naslov
An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid

Autori
Petrović Peroković, Vesna ; Ribić, Rosana ; Prugovečki, Biserka ; Matković-Čalogović, Dubravka ; Tomić, Srđanka

Izvornik
Croatica chemica acta (0011-1643) 85 (2012), 4; 419-423

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
adamantane; β-amino acid synthesis; nitrile reduction; crystal structure

Sažetak
Novel adamantane-containing β-amino acid, 2-(adamant-2-yl)-3-aminopropanoic acid, interesting from the aspect of medicinal chemistry, was prepared and characterized. It was synthesized in a sequence of three steps with very good overall yield. In the first step ethyl adamant-2-ylidenecyanoacetate was prepared and its crystal structure was determined. Reduction of this unsaturated cyanoacetate by catalytic hydrogenation gave the ethyl ester of the desired amino acid. 2-(Adamant-2-yl)-3-aminopropanoic acid was obtained following ester hydrolysis.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Projekti:
119-1191344-3121 - Sinteze i enzimske transformacije biološki aktivnih spojeva (Tomić-Pisarović, Srđanka, MZOS ) ( CroRIS)
119-1193079-1084 - Strukturno istraživanje bioloških makromolekula metodom rentgenske difrakcije (Matković-Čalogović, Dubravka, MZOS ) ( CroRIS)

Ustanove:
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Rosana Ribić (autor)

Avatar Url Dubravka Matković-Čalogović (autor)

Avatar Url Vesna Petrović-Peroković (autor)

Avatar Url Srđanka Tomić-Pisarović (autor)

Avatar Url Biserka Prugovečki (autor)

Poveznice na cjeloviti tekst rada:

doi Hrčak dx.doi.org

Citiraj ovu publikaciju:

Petrović Peroković, Vesna; Ribić, Rosana; Prugovečki, Biserka; Matković-Čalogović, Dubravka; Tomić, Srđanka
An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid // Croatica chemica acta, 85 (2012), 4; 419-423 doi:10.5562/cca2122 (međunarodna recenzija, članak, znanstveni)
Petrović Peroković, V., Ribić, R., Prugovečki, B., Matković-Čalogović, D. & Tomić, S. (2012) An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid. Croatica chemica acta, 85 (4), 419-423 doi:10.5562/cca2122.
@article{article, author = {Petrovi\'{c} Perokovi\'{c}, Vesna and Ribi\'{c}, Rosana and Prugove\v{c}ki, Biserka and Matkovi\'{c}-\v{C}alogovi\'{c}, Dubravka and Tomi\'{c}, Sr\djanka}, year = {2012}, pages = {419-423}, DOI = {10.5562/cca2122}, keywords = {adamantane, β-amino acid synthesis, nitrile reduction, crystal structure}, journal = {Croatica chemica acta}, doi = {10.5562/cca2122}, volume = {85}, number = {4}, issn = {0011-1643}, title = {An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid}, keyword = {adamantane, β-amino acid synthesis, nitrile reduction, crystal structure} }
@article{article, author = {Petrovi\'{c} Perokovi\'{c}, Vesna and Ribi\'{c}, Rosana and Prugove\v{c}ki, Biserka and Matkovi\'{c}-\v{C}alogovi\'{c}, Dubravka and Tomi\'{c}, Sr\djanka}, year = {2012}, pages = {419-423}, DOI = {10.5562/cca2122}, keywords = {adamantane, β-amino acid synthesis, nitrile reduction, crystal structure}, journal = {Croatica chemica acta}, doi = {10.5562/cca2122}, volume = {85}, number = {4}, issn = {0011-1643}, title = {An Efficient Synthesis of Novel Adamantane β-Amino Acid: 2-(Adamant-2-yl)-3-aminopropanoic Acid}, keyword = {adamantane, β-amino acid synthesis, nitrile reduction, crystal structure} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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