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Pregled bibliografske jedinice broj: 612232

Cytogenetic consequences after occupational exposure to antineoplastic drugs

Fučić, Aleksandra; Jazbec, Ana-Marija; Mijić, August; Šešo-Šimić, Đurđica; Tomek, Rudolf
Cytogenetic consequences after occupational exposure to antineoplastic drugs // Mutation research. Genetic toxicology and environmental mutagenesis, 416 (1998), 1/2; 59-66 doi:10.1016/S1383-5718(98)00084-9 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 612232 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Cytogenetic consequences after occupational exposure to antineoplastic drugs

Autori
Fučić, Aleksandra ; Jazbec, Ana-Marija ; Mijić, August ; Šešo-Šimić, Đurđica ; Tomek, Rudolf

Izvornik
Mutation research. Genetic toxicology and environmental mutagenesis (1383-5718) 416 (1998), 1/2; 59-66

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
antineoplastic drug ; biomonitoring ; chromosome aberration ; SCE ; micronucleus assay ; mitotic activity ; smoking ; occupational exposure

Sažetak
Cytogenetic monitoring was carried out on a group of 38 nurses who reconstitute antineoplastic drugs in order to determine the extent of chromosomal damage. Genotoxic activities of antineoplastic drugs are studied by chromosome aberration assay, micronucleus assay, sister chromatid exchange SCE frequency high frequency cells HFC analysis, and mitotic activity of peripheral lymphocytes. Results confirmed that occupational exposure to a mixture of antineoplastic drugs may cause genome damages. The results of this study show that biomonitoring after exposure to a mixture of antineoplastic drugs which express clastogenic and aneugenic activity should involve a battery of cytogenetic methods.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA

Projekti:
00220107
00220307

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Klinika za tumore,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb

Profili:

Avatar Url Aleksandra Fučić (autor)

Avatar Url Đurđica Šešo-Šimić (autor)

Avatar Url August Mijić (autor)

Avatar Url Rudolf Tomek (autor)

Poveznice na cjeloviti tekst rada:

doi dx.doi.org

Citiraj ovu publikaciju:

Fučić, Aleksandra; Jazbec, Ana-Marija; Mijić, August; Šešo-Šimić, Đurđica; Tomek, Rudolf
Cytogenetic consequences after occupational exposure to antineoplastic drugs // Mutation research. Genetic toxicology and environmental mutagenesis, 416 (1998), 1/2; 59-66 doi:10.1016/S1383-5718(98)00084-9 (međunarodna recenzija, članak, znanstveni)
Fučić, A., Jazbec, A., Mijić, A., Šešo-Šimić, Đ. & Tomek, R. (1998) Cytogenetic consequences after occupational exposure to antineoplastic drugs. Mutation research. Genetic toxicology and environmental mutagenesis, 416 (1/2), 59-66 doi:10.1016/S1383-5718(98)00084-9.
@article{article, author = {Fu\v{c}i\'{c}, Aleksandra and Jazbec, Ana-Marija and Miji\'{c}, August and \v{S}e\v{s}o-\v{S}imi\'{c}, \DJur\djica and Tomek, Rudolf}, year = {1998}, pages = {59-66}, DOI = {10.1016/S1383-5718(98)00084-9}, keywords = {antineoplastic drug, biomonitoring, chromosome aberration, SCE, micronucleus assay, mitotic activity, smoking, occupational exposure}, journal = {Mutation research. Genetic toxicology and environmental mutagenesis}, doi = {10.1016/S1383-5718(98)00084-9}, volume = {416}, number = {1/2}, issn = {1383-5718}, title = {Cytogenetic consequences after occupational exposure to antineoplastic drugs}, keyword = {antineoplastic drug, biomonitoring, chromosome aberration, SCE, micronucleus assay, mitotic activity, smoking, occupational exposure} }
@article{article, author = {Fu\v{c}i\'{c}, Aleksandra and Jazbec, Ana-Marija and Miji\'{c}, August and \v{S}e\v{s}o-\v{S}imi\'{c}, \DJur\djica and Tomek, Rudolf}, year = {1998}, pages = {59-66}, DOI = {10.1016/S1383-5718(98)00084-9}, keywords = {antineoplastic drug, biomonitoring, chromosome aberration, SCE, micronucleus assay, mitotic activity, smoking, occupational exposure}, journal = {Mutation research. Genetic toxicology and environmental mutagenesis}, doi = {10.1016/S1383-5718(98)00084-9}, volume = {416}, number = {1/2}, issn = {1383-5718}, title = {Cytogenetic consequences after occupational exposure to antineoplastic drugs}, keyword = {antineoplastic drug, biomonitoring, chromosome aberration, SCE, micronucleus assay, mitotic activity, smoking, occupational exposure} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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