Pregled bibliografske jedinice broj: 610912
Gene Knockout: the Technology of Gene Targeting
Gene Knockout: the Technology of Gene Targeting // Proceedongs of the Third Annual Conference for Biotechnology and Transplantation in Macedonia / Kokondoska, Vesna (ur.).
Skopje: Biotechnology Student Club, 2012. str. 11-22 (pozvano predavanje, domaća recenzija, cjeloviti rad (in extenso), znanstveni)
CROSBI ID: 610912 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Gene Knockout: the Technology of Gene Targeting
Autori
Mitrikeski, Petar Tomev
Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni
Izvornik
Proceedongs of the Third Annual Conference for Biotechnology and Transplantation in Macedonia
/ Kokondoska, Vesna - Skopje : Biotechnology Student Club, 2012, 11-22
Skup
Annual Conference for Biotechnology and Transplantation in Macedonia (3 ; 2012)
Mjesto i datum
Skopje, Sjeverna Makedonija, 22.09.2012
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Domaća recenzija
Ključne riječi
gene targeting; ends-out strategy; illegitimate recombination
Sažetak
The technology of gene knockout is based on gene targeting, a useful technique that utilizes homologous recombination to modify the genome of a living organism primordially developed in yeast Saccharomyces cerevisiae. During this process an in vitro engineered exogenous DNA fragment is transformed into a cell in order to permanently modify targeted genomic counterpart creating a selectable and heritable genomic change. This property allows extensive utilization of such a technological approach in both basic and applied research.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Biotehnologija
POVEZANOST RADA
Ustanove:
Institut za istraživanje i razvoj održivih eko sustava
Profili:
Petar Mitrikeski
(autor)
