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Pregled bibliografske jedinice broj: 607089

1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors

Micheli, Fabrizio; Cavanni, Paolo; Bettati, Michela; Bonanomi, Giorgio; Di Fabio, Romano; Fazzolari, Elettra; Marchioro, Carla; Roščić, Maja; Tarsi, Luca; Visentini, Filippo et al.
1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors // Bioorganic & medicinal chemistry, 19 (2011), 11; 3451-3461 doi:10.1016/j.bmc.2011.04.032 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 607089 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors

Autori
Micheli, Fabrizio ; Cavanni, Paolo ; Bettati, Michela ; Bonanomi, Giorgio ; Di Fabio, Romano ; Fazzolari, Elettra ; Marchioro, Carla ; Roščić, Maja ; Tarsi, Luca ; Visentini, Filippo ; Zonzini, Laura ; Worby, Angela

Izvornik
Bioorganic & medicinal chemistry (0968-0896) 19 (2011), 11; 3451-3461

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
triple re-uptake inhibitors; pharmacophore; SERT; NET; DAT

Sažetak
Further exploration around the recently disclosed potent triple re-uptake inhibitor 6-(3, 4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane led to the identification of a new series of potent triple re-uptake inhibitors endowed with good developability characteristics. The insertion of a further aryl moiety into the template allowed the ‘titration’ of the SERT/NET/DAT ratio leading to the identification of further tools in this important area.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti



POVEZANOST RADA

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com ac.els-cdn.com dx.doi.org

Citiraj ovu publikaciju:

Micheli, Fabrizio; Cavanni, Paolo; Bettati, Michela; Bonanomi, Giorgio; Di Fabio, Romano; Fazzolari, Elettra; Marchioro, Carla; Roščić, Maja; Tarsi, Luca; Visentini, Filippo et al.
1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors // Bioorganic & medicinal chemistry, 19 (2011), 11; 3451-3461 doi:10.1016/j.bmc.2011.04.032 (međunarodna recenzija, članak, znanstveni)
Micheli, F., Cavanni, P., Bettati, M., Bonanomi, G., Di Fabio, R., Fazzolari, E., Marchioro, C., Roščić, M., Tarsi, L. & Visentini, F. (2011) 1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors. Bioorganic & medicinal chemistry, 19 (11), 3451-3461 doi:10.1016/j.bmc.2011.04.032.
@article{article, author = {Micheli, Fabrizio and Cavanni, Paolo and Bettati, Michela and Bonanomi, Giorgio and Di Fabio, Romano and Fazzolari, Elettra and Marchioro, Carla and Ro\v{s}\v{c}i\'{c}, Maja and Tarsi, Luca and Visentini, Filippo and Zonzini, Laura and Worby, Angela}, year = {2011}, pages = {3451-3461}, DOI = {10.1016/j.bmc.2011.04.032}, keywords = {triple re-uptake inhibitors, pharmacophore, SERT, NET, DAT}, journal = {Bioorganic and medicinal chemistry}, doi = {10.1016/j.bmc.2011.04.032}, volume = {19}, number = {11}, issn = {0968-0896}, title = {1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors}, keyword = {triple re-uptake inhibitors, pharmacophore, SERT, NET, DAT} }
@article{article, author = {Micheli, Fabrizio and Cavanni, Paolo and Bettati, Michela and Bonanomi, Giorgio and Di Fabio, Romano and Fazzolari, Elettra and Marchioro, Carla and Ro\v{s}\v{c}i\'{c}, Maja and Tarsi, Luca and Visentini, Filippo and Zonzini, Laura and Worby, Angela}, year = {2011}, pages = {3451-3461}, DOI = {10.1016/j.bmc.2011.04.032}, keywords = {triple re-uptake inhibitors, pharmacophore, SERT, NET, DAT}, journal = {Bioorganic and medicinal chemistry}, doi = {10.1016/j.bmc.2011.04.032}, volume = {19}, number = {11}, issn = {0968-0896}, title = {1-Heteroaryl-6-(3, 4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane : Further insights into a class of triple re-uptake inhibitors}, keyword = {triple re-uptake inhibitors, pharmacophore, SERT, NET, DAT} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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