Naslov
High resolution computed tomography in evaluating lung involvement in connective tissue disease

Autori
Zekan Vučetić, Mirta:Mažuranić, Ivica:Marušić, Ante:Neralić-Meniga, Inja:Sertić-Milić, Helga:Peroš-Golubičić, Tatjana

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, stručni

Knjiga
Lung in non-pulmonary and systemic disease

Urednik/ci
Peroš-Golubičić, Tatjana

Izdavač
Medicinska naklada

Grad
Zagreb

Godina
2013

Raspon stranica
220-234

ISBN
978-953-176-577-0

Ključne riječi
High resolution computed tmograpy, pulmonary manifestations, connective tissue disease

Sažetak
High resolution computed tomography (HRCT) has become the golden standard for evaluating interstitial lung disease during last two decades. It by far surpasses the sensitivity and specificity of conventional chest radiographs in detecting the changes in pulmonary interstitium and airways, in non-invasive fashion. The connective tissue diseases are a diverse group of autoimmune, inflammatory disorders characterized by multiorgan involvement. When lungs are affected it usually involves pulmonary interstitium and small airways. HRCT plays an important role in the management of these patients, and HRCT patterns that appear in each of these disorders – rheumatoid arthritis, systemic sclerosis, polymyositis/dermatomyositis, systemic lupus erythematosus, Sjögren’s syndrome and mixed connective tissue disease are described in detail in this review. This is followed by a brief presentation of overall contribution of HRCT in the detection of these diseases, diagnosing, staging, follow-up and monitoring the treatment response, as well as its correlation with histopathological diagnosis. When HRCT is used as a part of multidisciplinary approach which should involve specialists in different fields evaluating patients with ILD together, it has been shown that HRCT is a helpful tool in reaching the correct final diagnosis, either when HRCT alone is sufficient to pose a specific diagnosis, or when it is used to direct surgical lung biopsy to the areas of lungs where the changes show the greatest density.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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