Naslov
Tissue-specific response of acid DNase activity in mussel Mytilus galloprovincialis exposed to mixed pollutants in sea-water organic extracts

Autori
Kovačić Ines, Perić Lorena, Fafanđel Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Archives of industrial hygiene and toxicology / Kopjar Nevenka - Zagreb : Institut za medicinska istraživanja medicinu rada-Institute for Medical Research and Occupational Health, 2012, 31-31

Skup
Croatian Congress of Toxicology (CROTOX) 2012

Mjesto i datum
Primošten, Hrvatska, 02.10.2012. - 05.10.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
mussel ; Acid DNase ; marine pollutant ; biomarker

Sažetak
New biomarkers of high sensitivity and low cost are widely investigated for marine biomonitoring purposes. Our previous investigations showed that the exposure of mussels to individual model marine pollutants causes the increase of acid DNase activity in hematocytes and hepatocytes indicating acid DNase activity as a promising biomarker. For further validation mussels were exposed to composite organic extracts of seawater from Adriatic (VRANJIC, industrial area – high potential toxicity, RIJEKA, harbor – moderate potential toxicity, PLOČE, small rural – low potential toxicity) and acid DNase activity was measured in gills and digestive gland. The patterns of influences in both tissues are site specific and related to different potential toxicity of sea-water extracts. In referent mussels acid DNase activity was higher in gills than in digestive gland. The extract from station with low potentional toxicity (PLOČE) did not induce statistically significant change the acid DNase activity in either tissue. Enzyme activity changed in gills of mussels exposed to extract with moderate potential toxicity (RIJEKA) and in digestive gland of mussels exposed to extracts with high potential toxicity (VRANJIC). In both cases enzyme activity increased already after 3 h, remained for 48 h and discriminate stations according to potential toxicity of organic extracts. Advantages/disadvantages of using acid DNase activity in mussel gills and/or digestive gland as biomarker of toxic pollutant presence are discussed.

Izvorni jezik
Engleski

Znanstvena područja
Geologija

POVEZANOST RADA