Naslov
Application of proteomics in biotechnology - Microbial proteomics

Autori
Josić, Djuro ; Kovač, Spomenka

Izvornik
Biotechnology Journal (1860-6768) 3 (2008), 4; 496-509

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Genomics ; Microbial proteomics ; Process development

Sažetak
The genomes of most economically important microbial cells are already sequenced and proteomic technologies can be applied during various process development steps, starting with the selection and optimization of the functions of the industrial strains, application of the knowledge of cell function in response to the changes of production parameters, validation of the downstream processing, and thorough characterization of the final product. Unfortunately, there are only a few direct examples in the literature that present the optimization of the production process based on proteomics. In this review, we discuss the potential of this technology for the design of future bioprocesses and for optimization of existing ones.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biotehnologija

Napomena
Special Issue: Novel Approaches to Drug Discovery
in Signal Transduction

POVEZANOST RADA