Naslov
The ACE-DD genotype distribution demonstrates possible age dependence among patients with diabetic nephropathy

Autori
Avdičević, Monika ; Krajina-Andričević, Mirna ; Zibar, Lada ; Štefanić, Mario ; Karner, Ivan ; Glavaš-Obrovac, Ljubica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
From Molecules to Life and back, FEBS3+ Meeting, 2012. Opatija, Croatia / - , 2012

Skup
FEBS 3+ Meeting

Mjesto i datum
Opatija, Hrvatska, 2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
diabetic nephropathy; diabetes mellitus type 2; angiotensine converting enzyme; polymorphism

Sažetak
Over the past few decades diabetes mellitus has expanded to epidemic size.Evidence for a genetic component to diabetic nephropathy comes from family studies displaying familial aggregation of diabetic nephropathy both in type 1 and type 2 diabetes mellitus, as well as differences in prevalence of diabetic nephropathy between etnic groups. An excess of DD genotype was found among patients with nephropathy younger than 66 years(45.3%) compared to those of the same age but with preserved renal function(22.9%).The difference is statisticaly significant( χ2=6.751 ; p=0.034).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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