Naslov
Proizvodnja heksanala u mikroreaktoru
(Hexanal production in the microreactor)

Autori
Šalić, Anita ; Zelić, Bruno

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Knjiga sažetaka: XIV. Ružičkini dani "Danas znanost - sutra industrija" / Jukić, Ante - Osijek : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2012, 79-79

ISBN
978-953-6894-46-8

Skup
XIV. Ružičkini dani "DANAS ZNANOST - SUTRA INDUSTRIJA"

Mjesto i datum
Vukovar, Hrvatska, 13.09.2012. - 15.09.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
mikrokanal; alkohol dehidrogenaza; heksanal
(microchannel; alcohol dehydrogenase; hexanal)

Sažetak
One of the most interesting pharmaceutical, agrochemical and aroma compounds are so called “green notes”. Hexanal is a part of that group. Several processes for the production of hexanal that are based on fermentation, extraction from plants and enzyme-catalyzed reactions have been described. However, due to low yields, formation of unwanted by-products and large quantities of waste, traditional methods cannot provide a sufficient amount of hexanal. Combination of microreactor technology and biotransformation could be a new solution for the production. Large surface to volume ratio, excellent mass and heath transfer, shorter residence time, smaller amount of reagents, catalyst and waste products comparing to equivalent bulk reactions, laminar flow, effective mixing and better process control, small energy consumption and less environmental impact are just some of the microsystem advantages. Implementation of microreactor technology for hexanal production is investigated in this study. Microreactors of different materials, e.g. glass and polytetrafluoroethylene (PTFE), suspended and immobilized enzyme alcohol dehydrogenase (ADH) isolated from baker yeast, and suspended and immobilized permeabilized yeast cells were used for hexanal production on microscale. Conversion of approximately 80 % for residence time of 72 s was observed in experiment with suspended ADH. For all investigated systems reaction kinetics was estimated and corresponding mathematical models were developed. Finally, the model prediction results were proven and verified on a set of independent experiments performed in a microreactor.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

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