Pregled bibliografske jedinice broj: 591875
In-vitro assessment of oxidative stress generated by orthodontic archwires
In-vitro assessment of oxidative stress generated by orthodontic archwires // American journal of orthodontics and dentofacial orthopedics, 141 (2012), 5; 583-589 doi:10.1016/j.ajodo.2011.11.020 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 591875 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
In-vitro assessment of oxidative stress generated by orthodontic archwires
Autori
Špalj, Stjepan ; Mlacović Zrinski, Magda ; Tudor Špalj, Vedrana ; Ivanković Buljan, Zorana
Izvornik
American journal of orthodontics and dentofacial orthopedics (0889-5406) 141
(2012), 5;
583-589
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
oxidative stress; genotoxicity; viability; orthodontic archwires
Sažetak
Several metals undergo redox cycling, producing free radicals and generating oxidative stress. The purpose of this study was to investigate in-vitro oxidative stress of orthodontic archwires made of various alloys. Mouse fibroblast cells L929 were exposed to 6 types of archwires, and the concentration of the oxidative stress marker 8-hydroxy-2'- deoxyguanosine in DNA was evaluated. Trypan blue dye was used in the determination of cell viability and numbers. Standard nickel- titanium archwires generated the highest oxidative stress, significantly higher than all other wires and the controls (P <0.05), and coated nickel- titanium, copper-nickel-titanium, and cobalt- chromium were lower than nickel-titanium (P <0.05), but higher than titanium-molybdenum and the negative and absolute controls (P <0.05). Titanium-molybdenum and stainless steel generated the lowest stress. Nickel-titanium induced the lowest viability, lower than the negative and absolute controls and all other wires (P <0.05) except titanium-molybdenum. Stainless steel showed the highest viability. Nickel-titanium produced the highest inhibition of cell growth, higher than all samples (P <0.05) except the positive control and cobalt-chromium. The lowest inhibition was observed in stainless steel and titanium- molybdenum, lower than nickel-titanium, cobalt- chromium, and the positive control (P <0.05). All orthodontic archwires generate oxidative stress in vitro. Stainless steel archwires have the highest and nickel-titanium the lowest biocompatibility.
Izvorni jezik
Engleski
Znanstvena područja
Dentalna medicina
POVEZANOST RADA
Projekti:
065-0650444-0436 - Nove dijagnostičke metode u ortodonciji i biokompatibilnost naprava (Šlaj, Mladen, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Rijeka,
Stomatološki fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE