Pregled bibliografske jedinice broj: 590218
Interaction of Spermine-Alanine Functionalized Perylene Bisimide Dye Aggregates with ds-DNA/RNA Secondary Structure
Interaction of Spermine-Alanine Functionalized Perylene Bisimide Dye Aggregates with ds-DNA/RNA Secondary Structure // Chemical Science, 3 (2012), 12; 3393-3397 doi:10.1039/c2sc20825c (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 590218 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Interaction of Spermine-Alanine Functionalized Perylene Bisimide Dye Aggregates with ds-DNA/RNA Secondary Structure
Autori
Rehm, Thomas H. ; Radić Stojković, Marijana ; Rehm, Stefanie ; Škugor, Marko ; Piantanida, Ivo ; Würthner, Frank
Izvornik
Chemical Science (2041-6520) 3
(2012), 12;
3393-3397
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
perylene bisimide; aggregates; DNA; RNA; CD spectropolyrimetry
Sažetak
We report for the first time on the interaction of self-assembled PBI dye aggregates with polynucleotides, revealing very high (nM) binding constants and exceptional thermal stabilization of double-stranded (ds)-DNA/RNA. Induced CD profiles of PBI dimer aggregates formed within DNA/RNA grooves show high sensitivity on the steric properties of the binding site, suggesting the applicability of such self-adjusting excitonically coupled PBI dimers for the sensing of the DNA/RNA secondary structure.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
098-0982914-2918 - Dizajn, sinteza i ispitivanje interakcija malih molekula s DNA, RNA i proteinima (Piantanida, Ivo, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
