Pregled bibliografske jedinice broj: 588208
Intraoral electrostimulator for xerostomia relief : a long-term, multicenter, open-label, uncontrolled, clinical trial
Intraoral electrostimulator for xerostomia relief : a long-term, multicenter, open-label, uncontrolled, clinical trial // Oral surgery, oral medicine, oral pathology, oral radiology, 113 (2012), 6; 773-781 doi:10.1016/j.oooo.2012.01.012 (međunarodna recenzija, članak, znanstveni)
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Naslov
Intraoral electrostimulator for xerostomia relief : a long-term, multicenter, open-label, uncontrolled, clinical trial
Autori
Alajbeg, Ivan ; Falcão, Denise P. ; Tran, Simon D. ; Martín-Granizo, Rafael ; Lafaurie, Gloria I. ; Matranga, Domenica ; Pejda, Slavica ; Vuletić, Lea ; Mantilla, Rubén ; Leal, Soraya C. ; Barreto Bezerra, Ana C. ; Ménard, Henri A. ; Kimoto, Suguru ; Pan, Shaoxia ; Maniegas, Lourdes ; Krushinski, Cheryl A. ; Melilli, Dario ; Campisi, Giuseppina ; Paderni, Carlo ; Bautista Mendoza, Gloria R. ; Yepes, Juan F. ; Lindh, Liselott ; Koray, Meltem ; Mumcu, Gonca ; Elad, Sharon ; Zeevi, Itai ; Aldape Barrios, Beatriz C. ; López Sánchez, Rodrigo M. ; Lassauzay, Claire ; Fromentin, Olivier ; Beiski, Ben Z. ; Strietzel, Frank P. ; Konttinen, Yrjö T. ; Wolff, Andy ; Zunt, Susan L.
Izvornik
Oral surgery, oral medicine, oral pathology, oral radiology (2212-4403) 113
(2012), 6;
773-781
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
xerostomia; intraoral saliva electrostimulator
Sažetak
A previous sham-controlled multinational study demonstrated the short-term efficacy and safety for xerostomia treatment of an intraoral device that delivers electrostimulation to the lingual nerve. The objective of this study was to test the hypothesis that those beneficial effects would be sustained over an 11-month period. The device was tested on a mixed sample of 94 patients with xerostomia in an open- label, uncontrolled, prospective multicenter trial. Statutory outcome assessments were done at 5th, 8th, and 11th months and analyzed by multiple comparisons. Improvements achieved at month 5 from baseline were sustained throughout the follow-up period for the primary outcome, xerostomia severity, and the secondary outcomes resting whole salivary flow rate, xerostomia frequency, oral discomfort, and difficulties in speech, swallowing, and sleeping. No significant side effects were detected. The beneficial effects of a removable intraoral electrostimulating device were sustained for an 11-month period.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Dentalna medicina
POVEZANOST RADA
Projekti:
065-0650445-1277 - Nearomatski naftalan –istraživanje sastava i bioloških učinaka na epitelna tkiva (Alajbeg, Ivan, MZOS ) ( CroRIS)
Ustanove:
Stomatološki fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE