Naslov
Impact of admission anemia, C-reactive protein and mean platelet volume on short term mortality in patients with acute ST-elevation myocardial infarction treated with primary angioplasty

Autori
Vrsalović, Mislav ; Pintarić, Hrvoje ; Babić, Zdravko ; Pavlov, Marin ; Vrsalović Presečki, Ana ; Getaldić, Biserka ; Vrkić, Nada ; Nikolić Heitzler, Vjeran

Izvornik
Clinical biochemistry (0009-9120) 45 (2012), 16-17; 1506-1509

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
anemia ; C-reactive protein ; mean platelet volume ; mortality ; myocardial infarction

Sažetak
Objectives were to investigate admission anemia, C-reactive protein (CRP) and mean platelet volume (MPV) together as prognostic markers in ST-elevation myocardial infarction (STEMI). Baseline hemoglobin, CRP and MPV were determined in 543 patients with acute STEMI to whom primary angioplasty was performed and evaluated for short term mortality (30days). After multivariate analysis anemia (odds ratio 2.69, 95% confidence interval 1.24-5.86) and CRP (odds ratio 3.40, 95% confidence interval 1.13-10.22) remained significant independent predictors of short-term mortality. Addition of anemia and CRP to PAMI risk score improved prediction of short-term outcome ; area under ROC curve rose from 0.76 to 0.87 (p<0.001). Better ability to determine 30-day mortality was obtained when anemia and CRP were incorporated into the PAMI risk score.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Farmacija

POVEZANOST RADA