Naslov
Biocompatibility of oxygen-plasma-treated polystyrene substrates

Autori
Vesel, Alenka ; Mozetič, Miran ; Jaganjac, Morana ; Milković, Lidija ; Čipak Gašparović, Ana ; Žarković, Neven

Izvornik
European physical journal-applied physics (1286-0042) 56 (2011), 2; 24024-1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
dense films; human mammary epithelial cells; non equilibrium; oxygen atom; oxygen plasmas

Sažetak
The biocompatibility of polystyrene (PS) samples has been improved by treatment with weakly ionized highly non-equilibrium oxygen plasma. Samples were exposed to plasma for 30 s for which they have received a dose of ions of 4.5 × 10 17 m -2 and a neutral oxygen atom dose of 3 × 10 -23 m -2. Both untreated and plasma-treated samples were tested for biocompatibility according to the same procedure. Proliferation of human mammary epithelial cells (HMECs) on samples revealed a dramatically improved biocompatibility of polystyrene treated by oxygen plasma. The HMECs were deposited on all samples and incubated for 1, 2 and 6 days. MTT test revealed about two times higher activity of cell enzymes after 48 h incubation. The activity for plasma-treated samples remained much higher than for untreated samples even after 6 days of incubation when the samples were already covered with a dense film of HMECs.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

Napomena
Topical Issue: : 18th International Colloquium on Plasma Processes (CIP 2011).

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