Naslov
Aspects for Genetic Predisposition - Qualitative Dermatoglyphic Analysis in Carcinomas

Autori
Pavićević, Radomir ; Miličić, Jasna ; Pavićević, Lukrecija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Bioinformatics and Genom Research / Kuhl, Phillips L. ; Lingham, Christina ; Katz, Jennifer - Baltimore (MD) : Cambridge Healthtech Institute (CHI), 1996, 5-5

Skup
Fifth International Bioinformatics and Genome Research

Mjesto i datum
Baltimore (MD), Sjedinjene Američke Države, 10.06.1996. - 11.06.1996

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
anthropology; population genetics; dermatoglyphic analysis; bronchopulmonary carcinomas

Sažetak
Dermatoglyphic traits are well suited for genetic studies because they are polygenetically determined and almost totally established and differentiated by the fourth fetal month, making them almost environmentally stable characters. While there seems to be general agreement that genetic factors play some role in the ethiopathogenesis of carcinoma, many important questions remain unresolved. The purpose of this investigation is to find out if differences between healthy controls and patients suffering of different types of carcinoma exist in qualitative dermatoglyphic with the aim of proving genetic predispositon of the carcinomas. Qualitative dermatoglyphic traits (whorls, loops and arches) on fingers and palms are studied in four different types of bronchopulmonary carcinoma in males and females and compared with healthy controls. Relative frequencies of whorls and loops on fingers differ in carcinoma planocellulare in males and in females. Hiernaux Dg biological distance in males show three separate clusters - first with carcinoma planocellulare, second with carcinoma microcellulare and third with adenocarcinoma, carcinoma macrocellulare and healthy controls. In females only breast carcinoma join in the same cluster with healthy controls, while all other carcinomas create a separate cluster. The largest distance is shown by adenocarinoma in females. The most common bronchopulmonary carcinoma - planocellulare differ in frequencies of patterns on fingers and palms in males and specially in females. Therefore, the endogenic factors are suspected to have important role in appearance of carcinoma planocellulare, as well as in most of other types of carcinoma.

Izvorni jezik
Engleski

Znanstvena područja
Etnologija i antropologija

POVEZANOST RADA