Naslov
Electrocardiographic changes in hospitalized patients with leptospirosis over a 10-year period

Autori
Škerk, Vedrana ; Puntarić, Hrvoje ; Delić-Brkljačić, Diana ; Markotić, Alemka ; Puljiz, Ivan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
4th National Meeting on Interventional Cardiology @ Fellow Course / - , 2011

Skup
4th National Meeting on Interventional Cardiology @ Fellow Course

Mjesto i datum
Dubrovnik, Hrvatska, 24.03.2011. - 27.03.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Leptospirosis; electrocardiographic changes

Sažetak
BACKGROUND: Leptospirosis is one of the common zoonosis of global distribution, caused by infection with pathogenic spirochetes of the genus Leptospira. Clinical reports make it clear that pericarditis, endocarditis, myocarditis and arrhythmias occur in leptospirosis. Cardiac involvement is correlated with the severity of disease. A few systematic studies for latent cardiac involvement in leptospirosis have been made. The aim of this study was to investigate the incidence and type of ECG changes in patients with leptospirosis regardless of clinical evidence of cardiac involvement. METHODS: A total of 97 patients with serologically confirmed leptospirosis treated at the University Hospital for Infectious Diseases „Dr. Fran Mihaljević“ in Zagreb, Croatia. Epidemiological and clinical data including main clinical characteristics and laboratory findings were obtained from hospital charts. The diagnosis was confirmed by microscopic agglutination test (MAT). A 12-lead resting ECG was routinely performed in the first 2 days after hospital admission when patients were febrile independent of the clinical manifestations. RESULTS: Abnormal ECG findings were found in 56 of 97 (58%) patients. Patients with abnormal ECG had significantly elevated values of bilirubin and alanine aminotransferase, lower values of potassium and lower number of platelets as well as more frequently recorded abnormal chest x-ray. All patients recovered completely. CONCLUSION: The ECG abnormalities are common at the beginning of disease and are possibly caused by direct effect of leptospires or are the non-specific result of a febrile infection and metabolic and electrolyte abnormalities.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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