Pregled bibliografske jedinice broj: 563093
Population attributable risk of tobacco and alcohol for upper aerodigestive tract cancer
Population attributable risk of tobacco and alcohol for upper aerodigestive tract cancer // Oral oncology, 47 (2011), 8; 725-731 doi:10.1016/j.oraloncology.2011.05.004 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 563093 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Population attributable risk of tobacco and alcohol for upper aerodigestive tract cancer
Autori
Anantharaman, D. ; Marron, M. ; Lagiou, P. ; Samoli, E. ; Ahrens, W. ; Pohlabeln, H. ; Slamova, A. ; Schejbalova, M. ; Merletti, F. ; Richiardi, L. ; Kjaerheim, K. ; Castellsague, X. ; Agudo, A. ; Talamini, R. ; Barzan, L. ; Macfarlane, T.V. ; Tickle, M. ; Simonato, L. ; Canova, C. ; Conway, D.I. ; McKinney, P.A. ; Thomson, P. ; Znaor, Ariana ; Healy, C.M. ; McCartan, B.E. ; Hashibe, M. ; Brennan, P. ; Macfarlane, G.J.
Izvornik
Oral oncology (1368-8375) 47
(2011), 8;
725-731
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Upper aerodigestive tract cancer; ARCAGE study; Population attributable risk; Tobacco; Alcohol
Sažetak
Tobacco and alcohol are major risk factors for upper aerodigestive tract (UADT) cancer and significant variation is observed in UADT cancer rates across Europe. We have estimated the proportion of UADT cancer burden explained by tobacco and alcohol and how this varies with the incidence rates across Europe, cancer sub-site, gender and age. This should help estimate the minimum residual burden of other risk factors to UADT cancer, including human papillomavirus. We analysed 1981 UADT cancer cases and 1993 controls from the ARCAGE multicentre study. We estimated the population attributable risk (PAR) of tobacco alone, alcohol alone and their joint effect. Tobacco and alcohol together explained 73% of UADT cancer burden of which nearly 29% was explained by smoking alone, less than 1% due to alcohol on its own and 44% by the joint effect of tobacco and alcohol. Tobacco and alcohol together explained a larger proportion of hypopharyngeal/laryngeal cancer (PAR=85%) than oropharyngeal (PAR=74%), esophageal (PAR=67%) and oral cancer (PAR=61%). Tobacco and alcohol together explain only about half of the total UADT cancer burden among women. Geographically, tobacco and alcohol explained a larger proportion of UADT cancer in central (PAR=84%) than southern (PAR=72%) and western Europe (PAR=67%). While the majority of the UADT cancers in Europe are due to tobacco or the joint effect of tobacco and alcohol, our results support a significant role for other risk factors in particular, for oral and oropharyngeal cancers and also for UADT cancers in southern and western Europe.
Izvorni jezik
Engleski
Znanstvena područja
Javno zdravstvo i zdravstvena zaštita
POVEZANOST RADA
Projekti:
005-1080315-0294 - Odrednice multiplih primarnih sijela raka u populaciji (Znaor, Ariana, MZOS ) ( CroRIS)
Ustanove:
Hrvatski zavod za javno zdravstvo
Profili:
Ariana Znaor
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE