Naslov
Detection of DNA damage in haemocytes of Zebra mussel using comet assay

Autori
Pavlica, Mirjana ; Klobučar, Goran I.V. ; Mojaš, Nina ; Erben, Radovan ; Papeš, Dražena

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of 30th Annual Meeting of European Environmental Mutagen Society / Gundy, Sarolta - Budimpešta : EEMS, 2000

Skup
30th Annual Meeting of European Environmental Mutagen Society

Mjesto i datum
Budimpešta, Mađarska, 22.08.2000. - 26.08.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
haemocytes; Zebra mussel; comet assay

Sažetak
The aim of this study was to evaluate the potential application of the comet assay on haemocytes of zebra mussel, Dreissena polymorpha Pall. for genotoxicity monitoring of freshwater environment. Zebra mussels were exposed for seven days to different concentrations (10, 80, 100 and 150 mg/l) of pentachlorophenol (PCP) and for one month in the River Sava, downstream from the municipal waste discharge of Zagreb town. The comet assay was conducted as described by Singh et al (1988) with slight modifications. Statisticaly significant increase in DNA single strand breakes was observed after exposure to 80, 100 and 150 mg/l of PCP and after exposure in the River Sava as well. Our study confirmed that the comet assay applied on zebra mussel haemocytes is very valuable in biomonitoring studies for determining the potential genotoxicity of water pollutants.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA