Naslov
False positive amphetamine finding

Autori
Sutlović, Davorka ; Veršić, Maja ; Definis-Gojanović, Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract of the 47th Congress of the European Societes of Toxicology (EUROTOX) Paris, France 28th-31st August 2011. / - , 2011

Skup
EUROTOX

Mjesto i datum
Pariz, Francuska, 28.08.2011. - 31.08.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
false positive amphetamine; GC-MS; postmortem liver

Sažetak
It has been noticed that the postmortem liver samples gives a positive result for amphetamines, although it is proved that the person has not previously consumed amphetamines. Postmortem liver samples are of great importance since they contain many valuable specimens in higher concentration then in some other biological samples. It was observed that liver tissue from persons found several days after death occur contains amphetamines. Purpose - The purpose of this study is to determine conditions that are responsible for amphetamine false positive finding in postmortem liver samples. Methods- Postmortem liver samples, which should be toxicologically processed, and the previous test gave negative amphetamine findings, are divided into several samples with identical weight and were subjected to the influence of different temperature in different time period. At various time intervals samples are being analyzed and determent qualitatively and quantitative by gas chromatography- mass spectrometry technique (GC/MS). Results - Liver samples with amphetamine negative findings, gave positive results after few days at temperature of 32, 5 degree Celsius. It was noted that the alcohol concentration has an effect on amphetamine occurrence.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija

POVEZANOST RADA