Naslov
Heart score in rural prehypertensives

Autori
Karanović, Sandra ; Jurić , Dragana ; Vuković Lela, Ivana ; Fištrek, Margareta ; Premužić , Vedran ; Cvitković , Ante ; Dika, Živka ; Kos , Jelena ; Čapkun , Vesna ; Laganović , Mario ; Fodor, Ljiljana ; Bitunjac , Milan ; Leko , Ninoslav ; Pećin , Ivan ; Jelaković, Bojan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of Hypertension Vol 29, e-Supplement A / - , 2011, 147-147

Skup
21st European Meeting on Hypertension and Cardiovascular Protection

Mjesto i datum
Milano, Italija, 17.06.2011. - 20.06.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
prehypertension ; heart score

Sažetak
Objective: Prehypertension is often accompanied with other metabolic disturbances that additionally increase cardiovascular (CV) risk. Our aim was to estimate total CV risk in prehypertension using European Heart Score. Design and Method: CV risk factors and Heart Score were analysed in 1375 subjects enrolled in epidemiologic survey conducted in rural part of Croatia. Treated hypertensives and individuals with acute illness, chronic terminal disease, pregnancy, dementia, immobility and those taking NSAID or corticosteroids were excluded. Blood pressure (BP) and heart rate were measured with OMRON device following ESH guidelines. Height, weight, body mass index (BMI), waist circumference (WC) and smoking status were determined. Fasting blood and urine samples were obtained for analysis of glucose (FBG), total (T-C), LDL and HDL cholesterol, triglycerides (TG) and urine albumin to creatinine ratio (ACR). European Heart Score was calculated. Subjects were divided into three groups regarding BP values: optimal BP (< 120/80) (OBP), prehypertension (120/80-139 /89) (PH), untreated hypertensives (≥ 140/90)(HT). ANOVA, Kruskal-Wallis and posthoc tests were used while the level of significance was set at < 0.05. Results: Four hundred ninety five subjects (216 men, 279 women), mean age 47.75 (range 19-90) were divided into three groups: OBP (N = 131), PH (N = 174), HT (N = 190). The percentages of smokers were 47.3%, 29.9% and 24.61% in OBP, PH and HT, respectively (p < 0.001). Significantly higher values of age, FBG, T-C, LDL, TG, BMI, WC and ACR (p < 0.001), and nonsignificantly higher values of HDL were found in HT vs PH. Significant differences in age, BMI, WC, T-C and LDL (p < 0.001) were found between PH and OBP while nonsignificantly higher values of FBG, TG and ACR were observed. As expected, Heart Score was highest in HT group (HT vs PH and OBP, p < 0.001). However, significant difference was also found in Heart Score between PH and OBP group (p < 0.001). Conclusion: Using Heart Score we found global CV risk to be significantly higher in PH than in OBP, indicating that PH should not be ignored, and beside life style changes in some subjects even drug therapy might be considered.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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