Naslov
Biodegredable Electrospun Material for Tissue Engineering

Autori
Mijović, Budimir ; Tominac Trcin, Mirna ; Agić, Ante ; Zdraveva, Emilija ; Bujić, Marina ; Spoljarić, Igor ; Košec, Vesna

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
TBIS 2011 - Textile Bioengineering and Informatics Symposium Proceedings on / Li, Yi ; Liu, Yuan-Feng ; Luo, Xiao-Nan ; Li, Jia-Shen - , 2011, 135-139

Skup
TBIS 2011 - Textile Bioengineering and Informatics Symposium Proceedings on “Advanced Textiles, Fashionable Industry”

Mjesto i datum
Peking, Kina, 27.05.2011. - 29.05.2011

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
PCL; NaOH Treatment; Keratinocytes; Fibroblasts; Cell Culture

Sažetak
The PCL known for its slow biodegradability offers advantageous possibilities for its applications in the field of skin scaffold production. In the current study PCL mats with micro scaled structure were produced via electrospinning and treated with NaOH solution for enhanced cell adhesion. The scaffolds were evaluated as an efficient stem cell growing material by human skin keratinocytes and fibroblasts culture. The cell viability assay (CellTiter-Blue) of the as spun scaffolds was compared to previously prepared PU electrospun scaffolds, fibrin scaffolds and amniotic membrane scaffold. Significant difference of cell adhesion was evident between the natural and synthetic scaffolds, as for the electrospun scaffolds the significance between, as well as for the NaOH treated samples was less evident. The repetitiveness of the different donor cells fluorescence within the same scaffold material was also present.

Izvorni jezik
Engleski

Znanstvena područja
Tekstilna tehnologija, Biotehnologija

POVEZANOST RADA