Naslov
Potential role of nickel in varicocele-associated infertility

Autori
Tariba, Blanka ; Pizent, Alica ; Živković, Tanja ; Čolak, Božo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of Trace Elements in Medicine and Biology 26(Suppl.1), Abstracts / Kruse-Jarres, Juergen D - : Elsevier, 2011

Skup
IX Congress of the International Society for Trace Element Research in Humans, Trace elements in health and disease: Essentiality, toxicity

Mjesto i datum
Belek, Turska, 16.10.2011. - 21.10.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
human semen quality; nickel; varicocele

Sažetak
Data on the reproductive effects of Ni are scarce and attention has usually been directed towards excessive exposure to this metal. Serum concentrations of As, Cd, Co, Cu, Hg, Mo, Ni, Pb, Se and Zn, parameters of semen quality and reproductive hormone levels were measured in samples collected from 76 men (age 24-46) with no occupational exposure to metals. The group consisted of 50 men with varicocele (an enlargement of the vein within the scrotum) and 26 control subjects. The results showed a significant deterioration in almost all measured semen quality parameters with increasing grade of varicocele. Men with varicocele had significantly higher concentrations of serum Ni. After adjusting for age, smoking habits, alcohol consumption and concentration of the other metals, the results showed that an increase in serum Ni significantly correlated with a decrease in sperm density, percentage and count of viable, motile and progressively motile sperm, and serum prolactin. These results indicate that even low-level Ni exposure may have adverse effects on male reproductive health.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA