Naslov
Value of β2-microglobulin in the serum of healthy subjects older than 40 years

Autori
Matoković, Damir ; Hašpl, Miroslav ; Petrić, Petar ; Škorvaga, Sanja ; Tomić Rajić, Marijana

Izvornik
Therapeutic apheresis and dialysis (1744-9979) 15 (2011), 3; 315-318

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
β2-microglobulin

Sažetak
The aim of this research was to determine if the age of healthy subjects older than 40 years of age has an influence on the concentration of β(2)-microglobulin in the serum of subjects of different populations. We examined the values of β(2)-microglobulin in the serum of 51 healthy subjects aged 40-86 years using the microparticle enzyme immunoassay AxSYM β(2) -microglobulin test. The reference values of β(2) -microglobulin according to the nonparametric statistical method is 0.95-2.73 mg/L. A correlation was found between β(2)-microglobulin and age: 40-50 years (0.94-1.54 mg/L), 51-65 years (0.96-2.62 mg/L), and >65 years (1.13-2.84 mg/L). There was no significant statistical difference of β(2)-microglobulin between genders (P > 0.05) ; however, there was a statistically significant difference between the concentration of β(2)-microglobulin and the subjects' age. (Spearman's rank correlation coefficient ρ = 0.66 ; P < 0.01). A direct correlation between age and the concentration of β(2)-microglobulin was observed. This research is a contribution to determining reference values of β(2)-microglobulin in subjects of different populations.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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