Naslov
Correlation of SF-36 physical domaine with measures of disease activity in patients with psoriatic arthritis

Autori
Grazio, Simeon ; Grubišić, Frane ; Vlak, Tonko ; Šošo, Daniela ; Nemčić, Tomislav ; Matijević Mikelić, Valentina ; Punda, Marija ; Skala, Hana ; Kusić, Zvonko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Annals of the Rheumatic Diseases vol.70 (suppl.3) / Kvein, Tore - : BMJ, 2011, 708-708

Skup
EULAR 2011 Annual Congress of the European League Against Rheumatism

Mjesto i datum
London, Ujedinjeno Kraljevstvo, 25.05.2011. - 28.05.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
psoriatic arthritis ; functional status ; illness index severity ; activity ; physical

Sažetak
Background: Psoriatic arthritis (PsA) can be associated with severe joint symptoms and with significant pain and stiffness, leading to chronic disability in performing activities of daily life. The correlation between SF 36 physical health and measures of disease activity has not been investigated. Objectives: To correlate SF-36 physical health (included general health) with measures of disease activity in PsA. Methods: One- hundred forty three consecutive adult patients of both genders (72 men, 71 women) with established diagnosis of PsA were enrolled in the study. Mean age was 57.75 10.91 years, the duration of PsA was 139.64 108.11 months and 35.7% of patients have never used DMARDs. SF-36 physical health included: physical functioning (PF), role limitations physical (RP), bodily pain (BP), and general health (GH). Disease activity was assessed using the following variables: tender joint count (TJC) (68 joints), swollen joint count (SJC) (66 joints), patient's global assessment (PtGA) (on VAS), examiner's global assessment (EGA) (on VAS), ESR (mm/hour) and CRP (mg/dl). Apart from descriptive statistics, Spearman's coefficient was used in order to investigate the correlations. Results were adjusted according to gender, age, and to the duration of PsA. The significance was set up at p=0.05. Results: The results for SF-36 were: PF 42.61±24.08, RP 19.66±32.23, BP 34.78±23.35 and GH 33.12±16.18. Significant correlations were found for SF-36 PF with TJC, SJC, PtGA, EGA and DAS, for SF-36 RP with TJC, and EGA, for SF-36 BP with TJC, PtGA, EGA, and DAS and for SF-36 GH with TJC, PtGA, and EGA. After adjustment, all correlations for SF-36 PF and SF- 36 BP were preserved. For SF-36 RP the result remained significant for PtGA, with the additional correlation with DAS, while for SF- 36 GH it retained significance only with TJC and PtGA Conclusions: In this cross-sectional study of patients with PsA correlations were found between SF-36 physical health domains and several parameters of disease activity, those of TJC and EGA seem being the most consistent ones.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA