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Pregled bibliografske jedinice broj: 543767

European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization

Hübel, K.; Fresen, M.M.; Apperley, J.F.; Basak, G.W.; Douglas, K.W.; Gabriel, I.H.; Geraldes, C.; Jakšić, Ozren; Koristek, Z.; Kröger, N. et al.
European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization // Bone marrow transplantation (Basingstoke), 47 (2011), 33-34 doi:10.1038/bmt.2011.216 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 543767 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization

Autori
Hübel, K. ; Fresen, M.M. ; Apperley, J.F. ; Basak, G.W. ; Douglas, K.W. ; Gabriel, I.H. ; Geraldes, C. ; Jakšić, Ozren ; Koristek, Z. ; Kröger, N. ; Lanza, F. ; Lemoli, R.M. ; Mikala, G. ; Selleslag, D. ; Worel, N. ; Mohty, M. ; Duarte, R.F.

Izvornik
Bone marrow transplantation (Basingstoke) (0268-3369) 47 (2011); 33-34

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Plerixafor

Sažetak
The effectiveness of the novel hematopoietic stem cell mobilizing agent plerixafor was evaluated in nationwide compassionate use programs in 13 European countries. A total of 580 poor mobilizers with non-Hodgkin's lymphoma (NHL), Hodgkin's lymphoma (HL) and multiple myeloma (MM) were enrolled. All patients received plerixafor plus granulocyte CSF with or without chemotherapy. Overall, the collection yield was significantly higher in MM patients (>2.0 × 10(6) CD34+ cells/kg: 81.6% ; >5.0 × 10(6) CD34+ cells/kg: 32.0%) than in NHL patients (>2.0 × 10(6) CD34+ cells/kg: 64.8% ; >5.0 × 10(6) CD34+ cells/kg: 12.6% ; P<0.0001) and also significantly higher in HL patients (>2.0 × 10(6) CD34+ cells/kg: 81.5% ; >5.0 × 10(6) CD34+ cells/kg: 22.2%) than in NHL patients (P=0.013). In a subgroup analysis, there were no significant differences in mobilization success comparing patients with diffuse large B- cell lymphoma, follicular lymphoma and mantle cell lymphoma. Our data emphasize the role of plerixafor in poor mobilizers, but further strategies to improve the apheresis yield especially in patients with NHL are required.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA

Projekti:
198-1980955-0953 - Imunobiologija kronične B-limfocitne leukemije i mikrookoliš (Jakšić, Ozren, MZOS ) ( CroRIS)

Ustanove:
Klinička bolnica "Dubrava"

Profili:

Avatar Url Ozren Jakšić (autor)

Poveznice na cjeloviti tekst rada:

doi www.nature.com

Citiraj ovu publikaciju:

Hübel, K.; Fresen, M.M.; Apperley, J.F.; Basak, G.W.; Douglas, K.W.; Gabriel, I.H.; Geraldes, C.; Jakšić, Ozren; Koristek, Z.; Kröger, N. et al.
European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization // Bone marrow transplantation (Basingstoke), 47 (2011), 33-34 doi:10.1038/bmt.2011.216 (međunarodna recenzija, članak, znanstveni)
Hübel, K., Fresen, M., Apperley, J., Basak, G., Douglas, K., Gabriel, I., Geraldes, C., Jakšić, O., Koristek, Z. & Kröger, N. (2011) European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization. Bone marrow transplantation (Basingstoke), 47, 33-34 doi:10.1038/bmt.2011.216.
@article{article, author = {H\"{u}bel, K. and Fresen, M.M. and Apperley, J.F. and Basak, G.W. and Douglas, K.W. and Gabriel, I.H. and Geraldes, C. and Jak\v{s}i\'{c}, Ozren and Koristek, Z. and Kr\"{o}ger, N. and Lanza, F. and Lemoli, R.M. and Mikala, G. and Selleslag, D. and Worel, N. and Mohty, M. and Duarte, R.F.}, year = {2011}, pages = {33-34}, DOI = {10.1038/bmt.2011.216}, keywords = {Plerixafor}, journal = {Bone marrow transplantation (Basingstoke)}, doi = {10.1038/bmt.2011.216}, volume = {47}, issn = {0268-3369}, title = {European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization}, keyword = {Plerixafor} }
@article{article, author = {H\"{u}bel, K. and Fresen, M.M. and Apperley, J.F. and Basak, G.W. and Douglas, K.W. and Gabriel, I.H. and Geraldes, C. and Jak\v{s}i\'{c}, Ozren and Koristek, Z. and Kr\"{o}ger, N. and Lanza, F. and Lemoli, R.M. and Mikala, G. and Selleslag, D. and Worel, N. and Mohty, M. and Duarte, R.F.}, year = {2011}, pages = {33-34}, DOI = {10.1038/bmt.2011.216}, keywords = {Plerixafor}, journal = {Bone marrow transplantation (Basingstoke)}, doi = {10.1038/bmt.2011.216}, volume = {47}, issn = {0268-3369}, title = {European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization}, keyword = {Plerixafor} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • MEDLINE

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  • MEDLINE

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