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Pregled bibliografske jedinice broj: 540761

Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum

Mosoarca, Cristina; Ghiulai, Roxana M.; Novaconi, Cristina R.; Vukelić, Željka; Chiriac, Adrian; Zamfir, Alina D.
Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum // Analytical letters, 44 (2011), 6; 1036-1049 doi:10.1080/00032719.2010.506938 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 540761 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum

Autori
Mosoarca, Cristina ; Ghiulai, Roxana M. ; Novaconi, Cristina R. ; Vukelić, Željka ; Chiriac, Adrian ; Zamfir, Alina D.

Izvornik
Analytical letters (0003-2719) 44 (2011), 6; 1036-1049

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
automation; cerebellum; chip-nanoelectrospray; gangliosides; ion trap mass spectrometry; NanoMate

Sažetak
Two native ganglioside mixtures from normal human fetal cerebellum in the 15th (Cc15)and 40th (Cc40) gestational week were subjected to NanoMate high capacity ion trap (HCT) mass spectrometric (MS) and collision induced dissociation (CID) tandem MS (MS2)analysis under thoroughly optimized experimental conditionns. An total of 56 different species were identified in Cc15 and 54 in Cc40. By employing CID MS2 molecular ions, related GD1 (d18:1/20:0) and GM2 (d18:1/19:0) species were structurally characterized in a high throughput mode. The method provided elevated ionization efficiency, high speed of analysis, almost 100% reproducibility at sample consumption per experiment situated in the femtomole range.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
108-1081870-2415 - Strukturno-funkcionalna glikolipidomika moždanog razvitka i maligne alteracije (Vukelić, Željka, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb

Profili:

Avatar Url Željka Vukelić (autor)

Poveznice na cjeloviti tekst rada:

doi dx.doi.org www.tandfonline.com

Citiraj ovu publikaciju:

Mosoarca, Cristina; Ghiulai, Roxana M.; Novaconi, Cristina R.; Vukelić, Željka; Chiriac, Adrian; Zamfir, Alina D.
Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum // Analytical letters, 44 (2011), 6; 1036-1049 doi:10.1080/00032719.2010.506938 (međunarodna recenzija, članak, znanstveni)
Mosoarca, C., Ghiulai, R., Novaconi, C., Vukelić, Ž., Chiriac, A. & Zamfir, A. (2011) Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum. Analytical letters, 44 (6), 1036-1049 doi:10.1080/00032719.2010.506938.
@article{article, author = {Mosoarca, Cristina and Ghiulai, Roxana M. and Novaconi, Cristina R. and Vukeli\'{c}, \v{Z}eljka and Chiriac, Adrian and Zamfir, Alina D.}, year = {2011}, pages = {1036-1049}, DOI = {10.1080/00032719.2010.506938}, keywords = {automation, cerebellum, chip-nanoelectrospray, gangliosides, ion trap mass spectrometry, NanoMate}, journal = {Analytical letters}, doi = {10.1080/00032719.2010.506938}, volume = {44}, number = {6}, issn = {0003-2719}, title = {Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum}, keyword = {automation, cerebellum, chip-nanoelectrospray, gangliosides, ion trap mass spectrometry, NanoMate} }
@article{article, author = {Mosoarca, Cristina and Ghiulai, Roxana M. and Novaconi, Cristina R. and Vukeli\'{c}, \v{Z}eljka and Chiriac, Adrian and Zamfir, Alina D.}, year = {2011}, pages = {1036-1049}, DOI = {10.1080/00032719.2010.506938}, keywords = {automation, cerebellum, chip-nanoelectrospray, gangliosides, ion trap mass spectrometry, NanoMate}, journal = {Analytical letters}, doi = {10.1080/00032719.2010.506938}, volume = {44}, number = {6}, issn = {0003-2719}, title = {Application of Chip-Based Nanoelectrospray Ion Trap Mass Spectrometry to Compositional and Structural Analysis of Gangliosides in Human Fetal Cerebellum}, keyword = {automation, cerebellum, chip-nanoelectrospray, gangliosides, ion trap mass spectrometry, NanoMate} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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