Naslov
Bacteria as a facultative symbiots of free-living amoebae

Autori
Šantić, Marina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
Sanitary engineering-Treći međunarodni stručno-znanstveni simpozij

Mjesto i datum
Opatija, Hrvatska, 10.11.2011. - 12.11.2011

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
bacteria; amoeba; intracellular life

Sažetak
Free-living amoebae such as Acanthamoeba and Hartmanella are environmental hosts of several intracellular pathogens such as Legionella, Chlamydia, and Mycobacterium. As most of these bacteria are pathogens of humans, amoebae have been suggested to act as "trojan horses" of microbial world. Since the host reservoir of F. tularensis in water system is not known we used H. vermiformis, which is the most predominant non-pathogenic amoeba in water resources, as an amebal model system to study the intracellular life of F. novicida. Our data indicate that F. novicida survives within H. vermiformis and that the bacteria do not escape into the cytoplasm, which is very distinct from the lifestyle of F. novicida within mammalian cells.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA