Naslov
Multiple Co-infections of Rodents with Hantaviruses, Leptospira and Babesia in Croatia

Autori
Tadin, Ante ; Turk, Nenad ; Korva, Miša ; Margaletić, Josip ; Beck, Relja ; Vucelja, Marko ; Habuš, Josipa ; Svoboda, Petra ; Avšič Županc, Tatjana ; Henttonen, Heikki ; Markotić Alemka

Izvornik
Vector-borne and zoonotic diseases (1530-3667) 12 (2012), 5; 388-392

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Babesia; Hantavirus; Leptospirosis; Rodent-borne; Zoonosis

Sažetak
Hantaviruses, Leptospira spp. and Babesia spp. are rodent-borne pathogens present worldwide. We studied multiple co-infections of small rodents in Croatia with all three pathogens. Twenty-eight Apodemus flavicollis and 16 Myodes glareolus were tested for the presence of hantavirus RNA by real time RT-PCR, Leptospira strains by renoculture method and Babesia DNA by PCR. Anti-hantavirus antibodies and anti-Leptospira antibodies were detected by serological methods. Very high infection prevalence with each pathogen was found in A. flavicollis – 20 of 28 rodents (71%) were infected with Dobrava virus, 13 rodents (46%) were infected with Leptospira and 5 rodents (18%) were infected with Babesia. Multiple co-infections with all three pathogens were found in 3 of 28 (11%) A. flavicollis suggesting that same rodent host can be infected with several pathogens at the same time. Dual infections with both hantaviruses and Leptospira were found in 7 of 44 rodents (16%), with hantaviruses and Babesia in 2 rodents (5%) and double infections with both Leptospira and Babesia were found in 1 rodent (2%). Since hantaviruses, Leptospira and Babesia have similar geographical distribution, it is to be expected that in other parts of the world multiple co-infections, which can represent possible high threat for public health, can be found.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Javno zdravstvo i zdravstvena zaštita, Veterinarska medicina

POVEZANOST RADA