Naslov
Chronic Budd-Chiari syndrome as a rare complication of Crohn's disease : a case report

Autori
Brinar, Marko ; Hrstić, Irena ; Čuković-Čavka, Silvija ; Štern-Padovan, Ranka ; Zupančić-Šalek, Silva ; Vucelić, Boris

Izvornik
European journal of gastroenterology & hepatology (0954-691X) 22 (2010), 6; 761-764

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Budd-Chiari syndrome ; Crohn's disease

Sažetak
The Budd-Chiari syndrome (BCS) is characterized by hepatic venous outflow obstruction involving the hepatic veins, inferior vena cava, or both. BCS has occasionally been reported in the literature as a very rare complication of ulcerative colitis. However, association of Crohn's disease (CD) and BCS is extremely rare with only a single case reported in the world literature to date. We report a case of a young woman with chronically active, therapy-resistant CD who developed massive ascites, elevation of liver enzymes, and coagulopathy in the course of her disease. She was subsequently diagnosed with BCS for which a successful liver transplantation was performed. Chronically active therapy resistant CD and methylenetetrahydrofolate reductase gene mutation have been identified as possible risk factors for development of BCS in this patient.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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