Pregled bibliografske jedinice broj: 535493
Cytogenotoxicity of sewage sludge leachate before and after calcium oxide-based solidification in human lymphocytes
Cytogenotoxicity of sewage sludge leachate before and after calcium oxide-based solidification in human lymphocytes // Ecotoxicology and environmental safety, 74 (2011), 5; 1408-1415 doi:10.1016/j.ecoenv.2011.04.008 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 535493 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Cytogenotoxicity of sewage sludge leachate before and after calcium oxide-based solidification in human lymphocytes
Autori
Gajski, Goran ; Oreščanin, Višnja ; Garaj Vrhovac, Vera
Izvornik
Ecotoxicology and environmental safety (0147-6513) 74
(2011), 5;
1408-1415
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Peripheral blood lymphocytes; Sewage sludge; Leachate; Solidification; Genome damage
Sažetak
Present study aimed to establish the chemical composition of sewage sludge leachate before/after calcium oxide-based solidification using energy dispersive X-ray fluorescence (EDXRF). The other aim was to determine leachate effects on human lymphocyte and DNA integrity in vitro using a battery of bioassays (DNA diffusion assay, micronucleus test and comet assay) to determine effects of those complex mixtures of elements on cell and DNA integrity. EDXRF showed that nickel concentration in the leachate of untreated sludge was 18.5 times higher than the upper permissible limit for inert waste landfills. Other elements were kept below the permissible values. After sludge solidification, leachate concentrations of Cr, Mn, Fe, Ni, Cu, Zn, and Pb dropped 1.6, 2.7, 37, 5.9, 3.2, 7.8, and 2.6 times, respectively. Untreated sludge leachate was cytogenotoxic to lymphocytes, and may lead to adverse effects on the exposed human populations, but calcium oxide-based solidification reduced these effects in significant manner.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
POVEZANOST RADA
Projekti:
022-0222148-2125 - Mutageni i antimutageni u ekogenetičkim istraživanjima (Garaj-Vrhovac, Vera, MZOS ) ( CroRIS)
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- EMBASE (Excerpta Medica)