Naslov
Toxicological relevance and potential risk due to polybrominated diphenylethers exposure

Autori
Ćurčić, Marijana ; Antonijević, Biljana ; Durgo, Ksenija ; Janković, Saša ; Jaćević, Vesna

Izvornik
Arhiv za farmaciju (0004-1963) 60 (2010), 3; 311-322

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
polybrominated diphenyl ethers; exposure; risk; chemicals management

Sažetak
Polybrominated diphenyl ethers (PBDEs) represent group of persistant organic chemicals (POPs), usually used as flame retardant additives in a variety of matherials and commercial products. Since 2009, PBDEs have been placed on the list of POPs chemicals, covered by Stockholm convention which is aimed to limit or ban production, use, emission, import and export of persistent organic pollutants, due to human health and environmental protection. Predominant routes of human exposure by PBDEs are ingestion by food, inhalation or dermal. Based on experimental studies, targets for PBDEs toxicity are nervous system, liver, thyroid gland and development. According to International Agency for Research on Cancer (IARC) PBDEs are not classified as a carcinogens, whereas according to Environmental Protection Agency (EPA) only deca BDE is classified as possible human carcinogen. So far, PBDEs have not been incoporated in national legislative framework. There are no data on environmental contamination, occupational exposure and exposure of general population. Therefore, placing the data on PBDEs in the focus of publics could contribute to the process of risk characterisation, and give directions for risk management in the Republic of Serbia.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

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