Naslov
Antraquinone Profile, Antioxidant and Antimicrobial Properties of Bark Extracts of Rhamnus catharticus and R. orbiculatus

Autori
Locatelli, Marcello ; Epifano, Franesco ; Genovese, Salvatore ; Carlucci, Giuseppe ; Zovko Končić, Marijana ; Kosalec, Ivan ; Kremer, Dario

Izvornik
Natural product communications (1934-578X) 6 (2011), 9; 1275-1280

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Rhamnus catharticus; Rhamnus orbiculatus; antraquinones profile; antioxidant

Sažetak
The anthraquinone profile, antioxidant and antimicrobial activities as well as the total flavonoid contents were were determined in methanol extracts of the barks of Rhamnus catharticus L. and R. orbiculatus Bornm. The most abundant anthraquinone derivates in R. catharticus were physcion (67.8%) and emodin (26.2%), while R. orbiculatus contained mostly physcion (81.3%) and chrysophanol (14.6%). R. catharticus displayed better activity in the ß-carotene-linoleic acid assay, as well as chelating activity, whereas its activity in the reducing power assay was significantly lower than that of R. orbiculatus. Both methanol extracts showed antimicrobial activity against all microbial species tested (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, Aspergillus niger, Microsporum gypseum) with MIC values either equal to or lower than 2.500 mg/mL. R. catharticus and R. orbiculatus contained several anthranoid aglycones and their bark extracts demonstrated notable antioxidant and antimicrobial properties. The results obtained indicate the medicinal potential of these two species.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Farmacija

POVEZANOST RADA