Naslov
Setting Research Priorities to Reduce Global Mortality from Childhood Pneumonia by 2015

Autori
Rudan, Igor ; El Arifeen, Shams ; Bhutta, Zulfiqar A. ; Black, Robert E. ; Brooks, Abdullah ; Chan, Kit Yee ; Chopra, Mickey ; Duke, Trevor ; Marsh, David ; Pio, Antonio ; Simoes, Eric A.F. ; Tamburlini, Giorgio ; Theodoratou, Evropi ; Weber, Martin W. ; Whitney, Cynthia G. ; Campbell, Harry ; Qazi, Shamim A. ; WHO/CHNRI Expert Group on Childhood Pneumonia

Kolaboracija
WHO/CHNRI Expert Group on Childhood Pneumonia

Izvornik
PLoS medicine (1549-1277) 8 (2011), 9; E1001099, 10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
health research priorities ; childhood pneumonia ; mortality ; United Nation's Millennium Development Goal 4

Sažetak
This paper aims to identify health research priorities that could assist the rate of progress in childhood pneumonia mortality reduction globally, as set out in the United Nation's Millennium Development Goal 4. The authors applied the Child Health and Nutrition Research Initiative methodology for setting priorities in health research investments. The process was coordinated by the World Health Organization. Forty-five leading childhood pneumonia researchers suggested more than 500 research ideas, which were merged into 158 research questions that spanned the broad spectrum of epidemiological research, health policy and systems research, improvement of existing interventions, and development of new interventions. Within the short time frame in which gains were expected globally, the research priorities were dominated by health systems and policy research topics (e.g., studying barriers to health care seeking and access, as well as barriers to increased coverage with available vaccines ; and evaluating the potential to safely scale up antibiotic treatment through community health workers). These were followed by epidemiological questions to identify the main gaps in knowledge (e.g., predictors of severe pneumonia that requires hospitalisation) ; priorities for improvement of the existing interventions (e.g., training of community health workers to recognise danger signs, refer, and treat sick children) ; and identifying cost reduction mechanisms for the available conjugate vaccines. Among the new interventions, the greatest support was shown for the development of low-cost conjugate vaccines and cross- protective common protein vaccines against the pneumococcus.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA