Naslov
One nodule is papillary carcinoma. What are the other nodules?

Autori
Mateša, Neven ; Moslavac, Sandra ; Kusić, Zvonko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Cytopathology, vol. 22, suppl. 1 / - , 2011, 99-99

Skup
36th European Congress of Cytopathology

Mjesto i datum
Istanbul, Turska, 22.09.2011. - 25.09.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Thyroid; Cytology

Sažetak
Aim: To investigate characteristics and clinical significance of nodules in multinodular thyroid if one nodule is papillary carcinoma (PC). Methods: We investigated 97 patients with a multinodular thyroid (proved by ultrasonography) and pathohistological diagnosis of PC. We assessed following variables: age and gender, FNA diagnosis, PC nodule size and dominance, intraglandular dissemination (ID), regional lymph node (RLN) status, and distribution of diagnoses of the other nodules. Results: Among 97 patients with PC (87 females and 10 males, median age 52), additional diagnoses were: 64 patients had nodular goiter (NG), 28 had ID, 26 had Hashimoto thyroiditis (HT), and 7 had follicular/Hürthle cell adenoma. 29 patients had more than one additional diagnosis. FNA diagnoses were PC or suspicious of PC in 95 patients, suspicious of follicular neoplasm in 1 patient, and inadequate material in one patient. Patients with additional NG or additional HT had a smaller average PC nodule size than patients without these diseases (13.2 or 12.9 vs. 15.2). PC nodule size positively correlated with the presence of RLN metastases (p<0.05). PC nodule was the dominant nodule in 64 patients (p<0.01). ID was more often in patients with a dominant PC nodule (p<0.01), and in patients without additional NG (p<0.01). Patients with ID (p<0.05), patients without NG (p<0.05), and patients without HT (p<0.05), had more often RLN metastases. Conclusion: Patients with PC and additional NG or HT had less often RLN metastases, probably due to smaller PC nodule size found during routine follow up of these benign diseases.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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