Naslov
Optically stimulated luminescence in vivo dosimetry for radiotherapy: physical characterization and clinical measurements in Co- 60 beams

Autori
Mrčela, Iva ; Bokulić, Tomislav ; Izewska, Joanna ; Budanec, Mirjana ; Frobe, Ana ; Kusić, Zvonko

Izvornik
Physics in medicine and biology (0031-9155) 56 (2011), 18; 6065-6082

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
In vivo dosimetry ; OSL ; radiotherapy

Sažetak
A commercial optically stimulated luminescence (OSL) dosimetry system was investigated for in vivo dosimetry in radiation therapy. Dosimetric characteristics of InLight dot dosimeters and a microStar reader (Landauer Inc.) were tested in 60Co beams. The reading uncertainty of a single dosimeter was 0.6%. The reproducibility of a set of dosimeters after a single irradiation was 1.6%, while in repeated irradiations of the same dosimeters it was found to be 3.5%. When OSL dosimeters were optically bleached between exposures, the reproducibility of repeated measurements improved to 1.0%. Dosimeters were calibrated for the entrance dose measurements and a full set of correction factors was determined. A pilot patient study that followed phantom validation testing included more than 100 measured fields with a mean relative difference of the measured entrance dose from the expected dose of 0.8% and the standard deviation of 2.5%. In conclusion, these results demonstrate that OSL dot dosimeters represent a valid alternative to already established in vivo dosimetry systems.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kliničke medicinske znanosti

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