Naslov
Comparison of needed end-tidal concentration of sevoflurane in children with balanced intravenous intraoperative analgesia versus epid ral caudal intraoperative analgesia: prospective randomized trial

Autori
Kremesec, Milena ; Štupnik, Špela ; Salihović, Mensur ; Marić, Stela ; Janković Novak, Vesna ; Paver Eržen, Vesna

Izvornik
Periodicum biologorum (0031-5362) 113 (2011), 2; 181-185

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
epidural caudal anaesthesia; sedative effects; sevoflurane; alfentanil; BIS; children

Sažetak
It was already shown that neuroaxial anaesthesia has sedative effects. The scope of our study was to find out whether the combined caudal epidural block with 0.19% bupivacaine decreases the sevoflurane requirement because of its synergistic hypnotic effect in comparison to balanced anaesthesia with intravenous alfentanil and sevoflurane in children. Forty boys aged 1–7 years were included in the study ; they were undergoing elective orchidopexy. Children were randomized in two groups: A (caudal block) and B (IV analgesia with opioid). Each child in group A received a caudal epidural block in a dosage of 0.19% bupivacaine 2.5 mg/kg. In group B the loading dose of alfentanil was 20 μg/kg, followed by intermittent doses of 10–20 μg/kg. Anaesthesia hypnosis was controlled by the clinical parameters and by the Bispectral Index monitor (BIS). We measured end-tidal sevoflurane concentration (sevoE) at 5-minute intervals. The aim was to maintain the BIS values near 50 through increments or decrements in sevoflurane concentration. No difference in end-tidal sevoflurane concentration (sevoE) values was observed between the two groups. We do suppose that due to the low level of caudal blockwe could not confirm synergism between caudal epidural block with local anaesthetic and sevoflurane.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA